Cyanosis

Last updated: Friday, 26, November, 2010
CausesAppropriate Tests
Initial clinical assessment; pathology tests as appropriate.
Peripheral cyanosis

Reduced peripheral perfusion

Cold related disorders

Central cyanosisBlood gases, co-oximetry, FBC, blood film.

Respiratory failure

Right to left shunts

  • Congenital heart disease

Methaemoglobinaemia

Methaemoglobin, sulphaemoglobin; Heinz body preparation
  • Nitrites
  • Sulphonamides

Haemoglobinopathy

  • Haemoglobin M

Identification of haemoglobin M including haemoglobin electrophoresis.

Further investigation - specialised laboratory.

Sulphaemoglobinaemia

See Methaemoglobinaemia, above.
  • Oxidant drugs