Helicobacter pylori infection

Last updated: Saturday, 04, December, 2010
Causal associationsAppropriate Tests

Endoscopy with gastric or duodenal biopsy (special stains) to identify Helicobacter  pylori; the urease test can be used for rapid identification of infection, but is less sensitive than histology.

Culture for sensitivity testing if recurrent or refractory disease.

Molecular genetics - microbial testing is available in some laboratories.

H. pylori antibodies provide evidence of infection, but are of limited value as a positive result does not distinguish past from current infection.

Antibody levels decline slowly after therapy.

Urease breath test can be used to identify continuing infection.

Peptic ulcer

Chronic atrophic gastritis

Gastric carcinoma

Gastric lymphoma