Herpes simplex infection
Last updated: Friday, 10, December, 2010
|Infection Sites||Appropriate Tests|
Clinical diagnosis, tests not usually required.
If infection is atypical, severe or recurrent: virus detection, culture - lesion swab or vesicle fluid.
Culture or PCR will distinguish HSV types I and II.
Although the diagnosis can be established by lesion biopsy, this should be avoided if possible as it may exacerbate the infection.
Herpes simplex virus antibodies (serum, CSF) are seldom usefulSee also Sexually transmitted diseases
Oesophageal biopsy may be necessary to distinguish HSV infection from candidiasis, CMV infection.
Virus detection, culture - CSF (including nucleic acid probe after PCR).
Usually only in neonates, immunodeficient patients.