Infection (increased susceptibility)
Last updated: Tuesday, 14, December, 2010
| Organisms | Appropriate Tests |
|---|---|
The causative organisms most frequently associated with the predisposing conditions are listed. | See also Immunodeficiency and Alcholoism |
Neutropenia | Infections are usually bacterial or fungal. See also Neutropenia and Febrile neutropenia. |
Pseudomonas aeruginosa | |
Escherichia coli | |
Klebsiella pneumoniae | |
Staphylococcus aureus | |
Streptococcus pyogenes | |
Candida spp | See Candidiasis. |
Aspergillus spp | See Aspergillosis. |
Mucor spp | See Mucormycosis. |
Cell mediated (T cell) immune dysfunction | Particularly in patients on steroid and immunosuppressive therapy (eg, fludarabine); in those with HIV infection; and following transplantation. Infections are commonly due to intracellular organisms, immunosuppressive treatment and steroid therapy. |
Herpes simplex | See Herpes simplex infection. |
Herpes zoster | See Varicella zoster infection. |
Cytomegalovirus | See Cytomegalovirus infection. |
Measles virus | See Measles. |
Mycobacterium spp | See Mycobacterial infection. |
Nocardia spp | See under Pneumonia - immunocompromised host. |
Salmonella spp | |
Legionella pneumophila | See under Pneumonia - atypical. See also Legionella infection |
Listeria monocytogenes | See Listeriosis. |
Cryptococcus neoformans | See Cryptococcal infection. |
Candida spp | See Candidiasis. |
Pneumocystis jiroveci | See under Pneumonia - immunocompromised host. |
Toxoplasma gondii | See Toxoplasmosis. |
Cryptosporidium sp | See Cryptosporidial infection. |
Strongyloides stercoralis | |
Humoral immune dysfunction | Deficient antibody production, particularly in patients with multiple myeloma, chronic lymphocytic leukaemia, nephrotic syndrome, and primary immunodeficiencies. |
Streptococcus pneumoniae | |
Haemophilus influenzae | |
Neisseria meningitidis | |
Giardia intestinalis | See Giardiasis. |
Complement deficiency and/or dysfunction | See under Immunodeficiency - primary. |
Streptococcus pneumoniae | See under Pneumonia. |
Neisseria meningitidis | |
Neisseria gonorrhoeae | |
Infections are commonly due to organisms of low virulence. |