Last updated: Monday, 25, October, 2010
Addisonian crisis (hypotension, hypovolaemia, hyperkalaemia; usually with hyponatraemia and hypoglycaemia) is a medical emergency and treatment should not be delayed pending hormone assay results.
Blood should be collected prior to treatment, for subsequent assay of cortisol and ACTH, to confirm or exclude the clinical diagnosis of adrenocortical insufficiency.
Synacthen stimulation test is the definitive test and may be required subsequently, if the initial test results are not diagnostic.
Primary (Addison’s disease)
Adrenal antibodies, thyroid antibodies, ovarian antibodies.
Polyglandular autoimmune candidiasis, including
See also AIDS.
Congenital adrenal hyperplasia
17-Hydroxyprogesterone; renin for monitoring mineralocorticoid replacement therapy.
Very long chain fatty acids.
Adrenal hypoplasia (X linked)
FNAB, if appropriate, after diagnostic imaging.