Last updated: Monday, 20, December, 2010
Endemic in SE Asia and northern Australia.
The clinical illness may be acute, sub-acute or chronic; reactivation of latent infection may occur. Localised infection may progress rapidly to septicaemia.
Blood culture, sputum microscopy and culture, wound swab, throat swab, rectal swab, urine (males) or tissue biopsy; Burkholderia pseudomallei antibodies are of only limited clinical utility.
Common sites include skin, lymph node, bone, brain, lung, myocardium and liver.
Chronic cavitating infection, which may be difficult to distinguish clinically from tuberculosis.