Renal tubulo-interstitial disorders
Last updated: Saturday, 29, January, 2011
Diagnosis guided by clinical context.
Biopsy may be required to establish underlying cause.
Baseline studies may include: electrolytes, creatinine, urea, calcium, phosphate, albumin; FBC.
Urine - microscopy. Urine acidification test only if significant renal tubular acidosis is suspected.
Water deprivation test if polyuria is clinically significant.
Renal biopsy if indicated.
See Analgesic abuse
Other drugs, especially
Antibiotic (aminoglycoside) assay.
Crystal nephropathy, especially
Urine - microscopy.
Drug hypersensitivity intertitial nephritis
Urine - microscopy (examination for eosinophils). Assay of immunoglobulin E is of no clinical value.
Medullary sponge kidney