Prolymphocytic leukaemia

Last updated: Tuesday, 21, December, 2010
Key InformationAppropriate Tests

FBC, blood film, differential WCC; immunophenotyping; protein (total), albumin, protein electrophoresis, paraprotein typing, immunoglobulins G, A, M.

Bone marrow aspiration and trephine biopsy.

A chronic lymphoid leukaemia in which massive splenomegaly and marked lymphocytosis are common. It is distinguished from chronic lymphocytic leukaemia (CLL) by the presence of >55% prolymphocytes on the blood film.

See also Chronic leukaemia and Lymphoproliferative disorders