Legionella sp antigen – bronchial washing

Last updated: Monday, 22, March, 2004

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Item Process
Specimen

Bronchial brushing, washing, lung biopsy, sputum.

Method

DFA.

Application

Investigation of severe or unresponsive pneumonia.

Interpretation

The presence of fluorescent bacilli on microscopy supports the diagnosis of legionella pneumonia.

The sensitivity and specificity of the test is low in sporadic pneumonia, but higher in epidemics. 

If available, detection of Legionella sp by nucleic acid detection after amplification (PCR) is the preferred test.

See also Legionella pneumophila serogroup 1 antigen - urine.

Reference

Murdoch DR. Clin Infect Dis 2003; 36: 64-69.