Schistosome antibodies

Last updated: Sunday, 28, May, 2006

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Item Process
Specimen

5-10 mL blood in plain tube.

Method

IF, EIA.

Reference Interval

IF titre <16.

Application

Provides support for the diagnosis of past or present infection with Schistosoma spp, when suspected because of exposure in an endemic area, and haematuria or other clinical features are present.

Interpretation

IF titres >16 support past or present infection. Returned travelers with a history of water exposure should not be tested until at least 12 weeks after the exposure.

In countries where schistosomiasis is endemic, the test can only be used to demonstrate exposure.

Demonstration of ova in tissue, faeces or urine provides a more specific indication of active infection.

Reference

Ross AGP et al. N Engl J Med 2002; 346: 1212-1220.