Jo-1 antibodies (Histidyl-tRNA synthetase antibodies) - serum
Last updated: Wednesday, 17, March, 2004
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| Item | Process |
|---|---|
| Specimen | 5 mL blood in plain tube. |
| Method | Immunoassay. |
| Reference Interval | Qualitative test. |
| Application | Diagnosis of polymyositis. |
| Interpretation | The presence of Jo-1 antibodies defines a subset of polymyositis with associated interstitial lung disease. It is present in a small proportion of patients with polymyositis alone. Autoantibodies against other t-RNA synthetases are also found in association with polymyositis. |
| Reference | Imbert-Masseau A. Joint Bone Spine 2003; 70(3): 161-168. |