Ovarian biopsy

Last updated: Monday, 05, April, 2004

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Item Process
Specimen

Fine needle aspiration biopsy, wedge biopsy or oophorectomy specimen.

Method

Blood collected pre-operatively for later evaluation of CA 125, alpha fetoprotein, carcinoembryonic antigen, inhibin, human chorionic gonadotrophic (ß subunit) if appropriate. 

Peritoneal washings (for cytology) and peritoneal biopsies (including the omentum) are required if clinical assessment or frozen section indicate malignancy.

Application

Evaluation of ovarian masses, which are often cystic, and may be inflammatory, infective or neoplastic.

Interpretation

Report from the pathologist identifies disease process, including tumour type, grade and stage. 

Serum markers may be helpful in monitoring tumour activity post operatively.

Reference

Robboy SJ et al. In: Kurman J ed. Blaustein's Pathology of the Female Genital Tract. 5th ed. Springer 2002.