Uterine cervix (cervical) biopsy

Last updated: Friday, 19, March, 2004

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Item Process

Punch or excision biopsy, biopsies from electrosurgical excision loop procedure (LEEP) or large loop excision of transformation zone (LLETZ), cone biopsy.


Fixed tissue in 10% buffered formal saline.


Investigation of abnormal smears. 

Diagnosis of HPV and other cervical infections. 

Assessment of epithelial hyperplasia and metaplasia, grading of epithelial dysplasia (CIN), diagnosis of invasive malignancy.


Report by pathologist identifies the nature of the lesion sampled. 

Tumour type, grade and stage are reported for neoplasms.


Robboy SJ et al. Pathology of the Female Reproductive Tract. Churchill Livingstone 2002.