Last updated: Monday, 22, March, 2004
Rarely used and only performed in specialised laboratories.
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5 mL blood in EDTA for 'direct' tests of neutrophil-bound antibody and 10 mL in plain tube for 'indirect' tests of antibody in serum
Direct and indirect immunofluoresence.
Investigation of neutropenia, when immune-mediated (including drug-induced) neutropenia is suspected.
A positive result is seen in immune neutropenia and drug-induced neutropenia eg, secondary to penicillins, cephalosporins, vancomycin.
Dacie JV and Lewis SM. Practical Haematology. 8th ed. Churchill Livingstone 1995.
Bux J and Mueller-Eckhardt C. Semin Haematol 1992; 29: 45-63.