Pyruvate kinase - red cell
Last updated: Friday, 02, April, 2004
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5 mL blood in ACD, lithium heparin, or EDTA tube.
Washed red cells are lysed. Assay performed at 37°C and results expressed as enzyme activity per gram of haemoglobin.
| Reference Interval|
Check with laboratory.
Investigation of non-spherocytic haemolytic anaemia.
Specific enzyme assay confirms deficiency.
Low levels confirm red cell pyruvate kinase deficiency.
Valentine WN et al. Ann Intern Med 1985; 103: 245-248.