Reptilase time
Last updated: Thursday, 25, March, 2004
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| Item | Process |
|---|---|
| Specimen | 4.5 mL blood added to 0.5 mL citrate. |
| Method | Reptilase is derived from the venom of Bothrops atrox, and clots fibrinogen by a mechanism different from that of thrombin. |
| Reference Interval | Consult laboratory. Typically <20 seconds. |
| Application | Investigation of patients with prolonged thrombin time. |
| Interpretation | Assists in differentiating the effect of heparin, presence of FDP and dysfibrinogenaemia. |
| Reference | Dacie JV and Lewis SM. Practical Haematology. 8th ed. Churchill Livingstone 1995. |