Unstable Haemoglobin screening test - blood
Last updated: Tuesday, 07, August, 2007
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| Item | Process |
|---|---|
| Specimen | 5 mL blood in any anticoagulant. |
| Method | Haemolysate made from washed red cells and examined for the presence of precipitate after incubation with isopropanol. |
| Reference Interval | Not detected. |
| Application | Investigation of haemolytic anaemia where unstable haemoglobinopathy is suspected. |
| Interpretation | Patients with an unstable haemoglobinopathy may have a chronic or intermittent haemolytic anaemia, or may have increased susceptibility to the haemolytic effects of oxidant drugs. |
| Reference | Winterbourn C. Semin Haematol 1990; 27: 41-50. |