Yersinia sp antibodies - serum

Last updated: Sunday, 28, May, 2006

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Item Process
Specimen

5-10 mL blood in plain tube.

Method

Immunoassay or agglutination.

Reference Interval

Not detected.

Application

Used to support the diagnosis of infection with Yersinia spp when cultures have been negative.

The test is of limited value because of false positives with infections caused by Brucella spp, Vibrio spp, E. coli and Salmonella spp and in patients with autoimmune thyroiditis.

Interpretation

Antibodies appear soon after onset of infection and may persist for six months.

A rise in titre between acute and convalescent sera increases the diagnostic significance of the test.

A negative result does not exclude the diagnosis.

Reference

Bottone EJ. Clin Microbiol Rev 1997; 10; 257-262.