Rheumatoid factor - serum
Last updated: Monday, 12, June, 2006
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5 mL blood in plain tube.
Nephelometry; turbidimetry. Agglutination of gamma globulin-coated latex particles or erythrocytes.
| Reference Interval|
Diagnosis and prognosis of rheumatoid arthritis.
Also positive in other chronic inflammatory conditions and immune complex diseases.
Patients with rheumatoid arthritis and positive rheumatoid factor tend to have more aggressive articular disease and are at greater risk of extra-articular complications.
Newkirk MM. J Rheumatol 2002; 29(10): 2034-2040.