Alpha-1-microglobulin - urine
Last updated: Wednesday, 07, April, 2004
MBS Online Search Page: Click here for details
| Item | Process |
|---|---|
| Specimen | Random urine. |
| Method | Immunoassay. An analyte/creatinine ratio is used to correct for varying dilution of urine. |
| Reference Interval | <15 mg/L; <1.5 g/mol creatinine. |
| Application | Diagnosis of tubular proteinuria (eg, Fanconi syndrome, tubulo-interstitial disorders). This test is preferable to β2-microglobulin as the latter is unstable in acid urine. |
| Interpretation | Increased excretion shows the presence of renal tubular disease. Increased levels may be present in the nephrotic syndrome but this is not invariable. |
| Reference | Everaert K et al. Clin Chim Acta 2000; 297(1-2): 183-189. |