Catecholamines - urine
Last updated: Monday, 06, August, 2007
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24 hour urine collection with HCl as preservative.
HPLC, radiometric assay.
| Reference Interval|
Adrenaline: <80 nmol/24 hours
|Application||Diagnosis of phaeochromocytoma (increased adrenaline and/or noradrenaline); diagnosis of neuroblastoma and ganglioneuroma (increased dopamine). For phaeochromocytoma plasma metanephrine may be preferred.|
Excretion of adrenaline and noradrenaline is usually increased in phaeochromocytoma, particularly after a hypertensive paroxysm.
Excretion may also be increased in malignant hypertension and with severe stress.
Some drugs (eg, labetalol) may interfere in some assays - consult pathologist.
Gerlo EAM and Sevens C. Clin Chem 1994; 40: 250-256.