Collagen crosslink fragments - urine
Last updated: Monday, 06, August, 2007
MBS Online Search Page: Click here for details
24 hour urine, random urine.
Results on random urine are expressed as a ratio with creatinine.
| Reference Interval|
Depends on method.
Diagnosis and monitoring of conditions with increased bone collagen breakdown, especially monitoring of treatment in patients with postmenopausal osteoporosis.
Deoxypyridinoline is specific for bone collagen. Pyridinoline can be derived from bone or tooth.
If excretion is increased it indicates an increase of bone breakdown.
Hannon RA and Eastell R. J Br Menopause Soc 2003; 9(1): 10-15.