Prostate specific antigen (PSA) - serum
Last updated: Friday, 04, June, 2010
The item number and fee shown are for Australia only. The fee is the Medicare Schedule Fee. Laboratories may charge above this fee in some circumstances.
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5 mL blood in plain tube.
| Reference Interval|
Depends on method and varies with age - consult pathologist.
Diagnosis and monitoring of prostatic carcinoma.
PSA has generally replaced acid phosphatase as it has greater sensitivity (especially for early invasive carcinoma) and specificity. The test is not recommended as a stand-alone screening test for carcinoma of the prostate.
The result should always be interpreted in conjunction with the findings on digital rectal examination and other clinical findings.
Marked elevation is indicative of carcinoma, but normal or slightly elevated PSA levels do not exclude it.
Nash AF and Meleginek I. Endocr Relat Cancer 2000; 7: 37-51.