Serotonin - platelet

Last updated: Friday, 26, March, 2004
Item Process
Specimen

5 mL blood in an EDTA tube.

The specimen must be delivered to the laboratory immediately after collection.

Some laboratories measure plasma or blood serotonin but platelets are the preferred specimen.

Method

HPLC.

Reference Interval

<5.4 nmol/109 platelets.

Application

Diagnosis of carcinoid syndrome.

Interpretation

Patients with carcinoid syndrome show elevation of platelet serotonin.

Reference

Oberg K. Expert Rev Anticancer Ther. 2003; 3(6): 863-877.