Vitamin D (1,25-dihydroxy) - serum
Last updated: Wednesday, 31, March, 2004
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| Item | Process |
|---|---|
| Specimen | 5 mL blood in a plain tube. |
| Method | Immunoassay. |
| Reference Interval | 35-120 pmol/L. |
| Application | Suspected abnormality of vitamin D, not affecting 25-hydroxycholecalciferol. The assay is rarely required clinically. |
| Interpretation | Normal levels of 25-hydroxycholecalciferol with increased 1,25-dihydroxycholecalciferol levels may be seen in patients with sarcoidosis and after excessive calcitriol intake. Low levels are seen in some forms of hereditary rickets. |
| Reference | Rosen JF and Chesney RW. J Pediatr 1983; 103: 1-17. Sharma OP. Curr Opin Pulm Med 2000; 6(5): 442-447. |