Vitamin D (25-hydroxy) - serum
Last updated: Wednesday, 31, March, 2004
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| Item | Process |
|---|---|
| Specimen | 5 mL blood in plain tube. |
| Method | Immunoassay. |
| Reference Interval | 40-160 nmol/L. |
| Application | Investigation of suspected rickets and osteomalacia (eg, malabsorption, dietary deficiency). Investigation of suspected vitamin D toxicity (hypercalcaemia, nephrocalcinosis, overdose). |
| Interpretation | Although 25-hydroxycholecalciferol is usually reliable for the diagnosis of abnormal vitamin D states, in a few instances (eg, sarcoidosis) 1,25-dihydroxycholecalciferol alone is abnormal. |
| Reference | Audran M. Mayo Clin Proc 1985; 60: 851-866. |