Lecithin-sphingomyelin (L/S) ratio - amniotic fluid
Last updated: Thursday, 22, April, 2004
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|Method||Thin layer chromatography. Some laboratories also measure phosphatidyl glycerol or count lamellar bodies.|
| Reference Interval|
L/S ratio >2.0 indicates fetal lung maturity.
Assessment of foetal lung maturity.
L/S ratio <2.0 indicates an increased risk of respiratory distress syndrome (RDS) at delivery.
L/S ratio <1.5 indicates a very high risk of developing RDS.
Babies of diabetic mothers can develop RDS with L/S ratios >2.0.
|Reference||Spillman T and Cotton DB. Crit Rev Clin Lab Sci 1989; 27: 341-389.|