Haemoglobin H inclusions

Last updated: Wednesday, 05, December, 2007
Item Process
Specimen

5 mL blood in EDTA tube.

Method

Fresh blood incubated with supravital stain; blood films examined for HbH inclusions.

Reference Interval

Not detected.

Application

Investigation of possible thalassaemia; characterisation and family studies of thalassaemias.

Interpretation

HbH inclusions can be found in the a thalassaemia traits and in haemoglobin H disease.

Reference

Working Party of the General Haematology Task Force of the British Committee for Standards in Haematology. Br J Haematol 1998; 101: 783-792.