Glomerular basement membrane antibodies - serum
Last updated: Monday, 22, March, 2004
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| Item | Process |
|---|---|
| Specimen | 5 mL blood in plain tube. |
| Method | Immunoassay, indirect IF. |
| Reference Interval | Not detected. |
| Application | Diagnosis of Goodpasture syndrome . Assessment of rapidly progressive glomerulonephritis. |
| Interpretation | Glomerular basement membrane antibodies are highly predictive of Goodpasture syndrome; the definitive diagnosis of Goodpasture syndrome requires renal biopsy with IF. |
| Reference | Jindal, Kailash K.. Management of idiopathic crescentic and diffuse proliferative glomerulonephritis: Evidence-based recommendations. Kidney International - Supplement. Management of Glomerulonephrilis. 55 Supplement No. 70:S-33-S-40, June 1999. |