Glomerular basement membrane antibodies - serum

Last updated: Monday, 22, March, 2004

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Item Process
Specimen

5 mL blood in plain tube.

Method

Immunoassay, indirect IF.

Reference Interval

Not detected.

Application

Diagnosis of Goodpasture syndrome . Assessment of rapidly progressive glomerulonephritis.

Interpretation

Glomerular basement membrane antibodies are highly predictive of Goodpasture syndrome; the definitive diagnosis of Goodpasture syndrome requires renal biopsy with IF.

Reference

Jindal, Kailash K.. Management of idiopathic crescentic and diffuse proliferative glomerulonephritis: Evidence-based recommendations. Kidney International - Supplement. Management of Glomerulonephrilis. 55 Supplement No. 70:S-33-S-40, June 1999.