Heat shock protein 70 antibodies

Last updated: Monday, 22, March, 2004

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Item Process
Specimen

5 mL blood in plain tube.

Method

Western blot.

Reference Interval

Consult pathologist.

Application

Of some value in delineating a group of patients with idiopathic progressive bilateral sensorineural hearing loss who may be responsive to immunosuppressive therapy.

Interpretation

Between 20-70% of patients with idiopathic sensorineural hearing loss will be positive for this antibody.

Approximately 30% of patients with Meniere's disease will also be positive.

Reference

Billings PB. Ann Otol Rhinol Laryngol 1995; 104: 181-188.